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Q1: Instructions: Introduction 3D printing in the drug delivery This is the TOPIC; we need to prepare PPT on. Introduction part must include MECHANISM. 3 slides PPT, with speaker notes. 30 words per slide. HARVARD REEFERENCING STYLE.See Answer
Q2: To/Do Need to Write 2 pages about 3 life style modifications for a person with elevated blood pressure, smoker, no physical activities, overweight . APA7 Format Read the SOAP note, the person also is a smoker and has a family history of heart disease, all the information is in the SOAP note./n Ohio University Advanced Pharmacology Case Study Module 1 SOAP Bob Cat Module 1 New patient HTN Demographics: • Patient Name: Bob Cat • Age: 50 • Gender: Male Subjective: • Past Medical History: None • Current Medications: None • Surgical History: None • Allergies: Penicillin, tree nuts Social History: • Smoking Status: Current smoker, averaging 1 pack per day for the past 20 years • Alcohol: Occasionally consumes 1-2 beers with dinner • Diet: Strives to eat healthy with no specific diet • Exercise: Rarely engages in physical activity • Family History: Father passed away at 65 due to heart failure, mother currently 80 and well, no family history of cancer, only child Chief Complaint: "I haven't seen a provider in about 20 years, so I'm here to see you as my new PCP." Review of Systems (ROS): • Constitutional: Denies fevers, chills, sweats, and weight changes. • Eyes: Denies any visual symptoms, eye pain, crusting, or drainage. • Ears, Nose, and Throat: No difficulties with hearing. No symptoms of rhinitis or sore throat. Cardiovascular: Denies chest pains, palpitations, orthopnea, paroxysmal nocturnal dyspnea, or extremity edema. • Respiratory: No dyspnea on exertion, no wheezing or cough. Gl: No nausea, vomiting, diarrhea, constipation, abdominal pain, hematochezia, or melena. Ohio University Advanced Pharmacology Case Study Module 1 GU: No urinary hesitancy or dribbling. No nocturia or urinary frequency. No abnormal urethral discharge. Musculoskeletal: No myalgias or arthralgias. Neurologic: No chronic headaches, no seizures. Patient denies numbness, tingling, or weakness. • Psychiatric: Denies problems with mood disturbance. No problems with anxiety. • Endocrine: No excessive urination or excessive thirst. • Dermatologic: Denies any rashes or skin changes. Objective: • Vitals: • Height: 5' 10" • Weight: 190 lbs • BMI: 26 • Temperature: 97.8°F • Blood pressure: 148/94 (recheck 150/88) Heart rate: 70 SPO2: 98% Pain: 0 Physical Exam: • General: Well-appearing, well-nourished, in no distress. Oriented x 3, normal mood, and affect. Ambulating without difficulty. Skin: Good turgor, no rash, unusual bruising, or prominent lesions. Normal hair texture and distribution. Nails exhibit normal color with no deformities. • HEENT: Normocephalic, atraumatic head. Eyes show intact visual acuity, clear conjunctiva, non-icteric sclera, and normal fundi. Ears have clear ear canals, translucent • and mobile tympanic membranes. Nose and mouth exhibit no abnormalities. Neck: Supple, without lesions, bruits, or adenopathy. Non-enlarged and non-tender thyroid. Cardiovascular: No cardiomegaly or thrills; regular rate and rhythm, no murmur or gallop. Ohio University Advanced Pharmacology Case Study Module 1 • • • • Respiratory: Clear to auscultation and percussion, no wheezes, rhonchi, or crackles. Abdomen: Normal bowel sounds, no tenderness, organomegaly, masses, or hernia. Back: Normal spine without deformity or tenderness, no CVA tenderness. Extremities: No amputations or deformities, cyanosis, edema, or varicosities. Peripheral pulses intact. Neurological: CN 2-12 normal, normal sensation to pain, touch, and proprioception. Normal deep tendon reflexes, no pathologic reflexes. Psychiatry: Oriented X3, intact recent and remote memory, judgment, insight, normal mood, and affect. G/U: Circumcised penis without lesions, normal urethral meatus without discharge, normal-sized testes and epididymides. Assessment: 1. Z00.00 Well Adult Exam 2. R03.0 - Elevated blood-pressure reading, without diagnosis of hypertension 3. F17.200- Smoker 20-year pack history Plan: 1. Z00.00 Well Adult Exam - • Labs ordered include CBC, CMP, TSH, A1C, Lipid panel. • Counseled on age-related screenings; colonoscopy ordered. • Administered PCV15 pneumonia vaccine. 2. R03.0 - Elevated blood-pressure reading, without diagnosis of hypertension Initial elevated blood pressure reading. Follow-up scheduled in one week. ***STUDENT TO PRESCRIBE LIFESTYLE MODIFICATIONS*** 3. F17.200-Smoker 20-year pack history • Counseled on smoking cessation; patient not currently ready to quit.See Answer
Q3:/n COMPANY NAME BATCH MANUFACTURING RECORD Page: 1 of 8 Department: Production Title : Tongkat Ali Tablet Batch Record : BMR-001 Name Prepared by: Production Manager Approved by: QA Manager Signature Date Revision No. : 0 Effective Date : 1 January 201 1. Product Details Description Batch Quantity Packaging Storage Conditions Tongkat Ali 250mg Tablet Colour: Pale Shape: Round/ Biconvex Batch size: 53 kg Approx No. tablets: Bottle of 60's - Ambient conditions, store in tight container protected from light and moisture 2. Production Batch Record Issuance Issued By - Issuer has reviewed the Batch Record to ensure that the copy is a complete, accurate copy of the Master Batch Record. (Print) Issued By - Quality Assurance Signature Date Issued To - Production has reviewed the Batch Record to ensure that the copy is a complete and correct. Production is responsible for the Batch Record following issuance. (Print) Issued By – Quality Assurance Signature 3. Reference Documents SOP 002: Non conformances SOP 007: Line Clearance - SOP-010: Temperature and Humidity Monitoring SOP-012: Facility Cleaning Procedures SOP 015: Material Weighing and Dispensing - SOP-017: Batch Manufacturing Records - SOP 019: Tray Oven SOP-021: Grinding and Milling Machine SOP 022: Cadmill - SOP - 023: Cube Mixer Batch No: TT 1606001 Manufacturing Date: 10 July 2016 Expiry Date: 9 July 2017 Date COMPANY NAME BATCH MANUFACTURING RECORD Page: 2 of 8 Department: Production Title : Tongkat Ali Tablet Batch Record : BMR-001 Name Prepared by: Production Manager Approved by: QA Manager SOP 028: Ribbon Mixer SOP 032: B2 Strokes Tablet Press 4. Raw Materials Signature Date Revision No. : 0 Effective Date : 1 January 2016 Quantity Part Description Required Lot No. Qty Staged Number Exp/ Retest Performed By/Date Verified By / Date (kg) Eurycoma R-0122 25.00 Longifolia Lactose R-2323 19.34 Monohydrate Gelatin R-7896 4.80 Corn Starch R-5858 2.40 Methocel R-0326 1.00 Magnesium R-9696 0.46 Stearate BP/USP 5. Processing Equipments Equipment Description ID No. Previous Calibration Calibration Required Performed By / Date Verified By / Date Weighing Balance 150 kg WB-01 Tray Oven OT-01 Grinding and Milling GM-01 Machine Cube Mixer MX-03 Ribbon Mixer MX-02 Cadmill GM-02 B2 Strokes Tablet Press TP-01 Stainless Steel Container CS-03 Mechanical Sieve (Mesh No: 12) SM-01 6. Area Clearance Batch No: TT 1606001 Manufacturing Date : 10 July 2016 Expiry Date: 9 July 2017 COMPANY NAME BATCH MANUFACTURING RECORD Page: 3 of 8 Department: Production Title : Tongkat Ali Tablet Batch Record : BMR-001 Name Signature Date Prepared by: Production Manager Approved by: QA Manager Step 1. GMP Processing Area(s): Room: 2. Review the GMP Processing Area Logbook(s) and ensure that the Logbook(s) is (are) complete, and up-to-date. 3. Review all applicable GMP Processing Area Logbook(s) and verify that Cleaning has been performed according to Facility Cleaning Procedures (SOP-011) Date Cleaning Complete: 4. Review Section 4: Raw Materials, and ensure that it is complete, accurate, and that all necessary materials are present for the GMP operation. 5. Ensure that all GMP Materials are Released, Approved and have sufficient time to the Expiry Date. 6. Review Section 5: Processing Equipment, and ensure that it is complete, accurate, and that all necessary equipment is present, cleaned and calibrated, as appropriate. 7. Review the Logbook for each piece of Equipment, and ensure that the Logbooks are correctly filled out. Tray Oven (OT-01) Grinding and Milling Machine (GM-01): Cube Mixer (MX-03) Ribbon Mixer (MX-02) B2 Strokes Tablet Press (TP-01) 8. Verify that the Production Area does not contain any items from previous batches or cleaning activities and that no items unrelated to the current batch are present. 9. Area Clearance Complete. QA shall Complete the Area Clearance Sign (SOP-007, Attachment 1) and affix it to the GMP Processing Area entrance. Batch No: TT 1606001 Revision No. : 0 Effective Date : 1 January 2016 Performed By / Verified By / Date Date Manufacturing Date : 10 July 2016 Expiry Date: 9 July 2017 COMPANY NAME BATCH MANUFACTURING RECORD Page: 4 of 8 Department: Production Title : Tongkat Ali Tablet Batch Record : BMR-001 Name Signature Date Prepared by: Production Manager Approved by: 7. Production Procedure Processing Step QA Manager A. Dispensing & Raw Material Preparation Location: Dispensing Room 1 1. Ensure room Temperature is within 22-24°C and Humidity is less than 65% 2. Weigh the ALL Raw Materials (RM) as mentioned in Part 4 separately into a suitable container/ plastic bags in. Label each of the container/ bags with a) Name of RM b) Lot No. 3. Wash Eurycoma longifolia (Tongkat Ali) with RO water and dry in Tray Oven (ID: OT-01) at 60°C for 8 hours. Temperature: °C Time Start: Time Stop: 4. Crush/powder the dry Eurycoma longifolia (Tongkat Ali) into fine powder with Grinding and Milling Machine (ID: GM-01). B. Mixing Location: Mixing Room 2 5. Ensure room Temperature is within 22-24°C and Humidity is less than 65% Revision No. : 0 Effective Date : 1 January 2016 Performed By/Date Verified By / Date Temperature: Humidity: 6. Mix Eurycoma longifolia powder, Lactose and Corn Starch in Cube Mixer (ID: MX-03) for 5 mins. Time Start: Time Stop: 7. Transfer all the contents of Cube Mixer (ID: MX-03) into a suitable container/plastic bags. 8. Label the plastic bag with a) "Tongkat Ali A Blend" Batch No: TT 1606001 Manufacturing Date : 10 July 2016 Expiry Date: 9 July 2017 COMPANY NAME BATCH MANUFACTURING RECORD Page: 5 of 8 Department: Production Title : Tongkat Ali Tablet Batch Record : BMR-001 Name Prepared by: Production Manager Approved by: QA Manager Signature Date Revision No. : 0 b) Batch No. 9. "Transfer Tongkat Ali A Blend” into Ribbon Mixer (ID: MX-02). 10. Blend for 3 mins at speed no: 3. Speed No: Time Start: Time Stop: 11. Dissolve Gelatin with hot water in a Stainless Steel Container (ID: CS- 03). 12. Pour the "Dissolved Gelatin" into the powder, granulate for 5 mins at speed no: 3.. Speed No: Time Start: Time Stop: 13. Transfer all the contents of Ribbon Mixer (ID: MX-02) into Cadmill (ID: GM-02). Operate the machine according the SOP-022. 14. Dry the granules at 60°C for 6 hours in Tray Oven (ID: OT-01). Temperature: °C Time Start: Time Stop: 15. Sieve into fine powder with Mechanical Siever (Mesh No: 12) 16. Transfer the fine powder into Cube Mixer (ID: MX-03), add in Magnesium Stearate and mix for 10 minutes at speed no: 3. Speed No: Time Start: Time Stop: 17. Transfer the contents of the Cube Mixer into a suitable plastic bag. 18. Label the plastic bag a) "Blend for Tableting: Tongkat Ali❞ b) Batch No C. Tableting 19. Ensure room Temperature is within 22-24°C and Humidity is less than 65% Temperature: Batch No: TT 1606001 Humidity: Manufacturing Date : 10 July 2016 Expiry Date: 9 July 2017 Effective Date : 1 January 2016See Answer
Q4: OSCE exam for counselling using check list There are 2 works on two topic smoking cessation and and elderly care client has provided sample for both works we have to change the scenario according to the topic and Create Question using the 5 A's of counselling and also answer that Qs in 500 - 1000 words and need to follow and complete the checklist attached of 5 A's In both work out of 5A- 5As model (ask, advice, asses, assist and arrange) you need to select 2 A's only || For smoking part you can create the question using Ask and assist and follow the same thing for elderly work. Student instructions :: 1.} I need to conduct an exam for medical students on the subject of smoking cessation using a checklist in the form of an OSCE. Can you do that? 2.} we have 5As model (ask, advice, asses, assist and arrange) from these I need tutor make case senarion for person came to smoking cessation clinic and he want to quitt smoking, this is called counselling and we have to start with patient by 5 As 3.} In exam I need to choose only 2 As to discuss with student using checklist 4.} Objective structured clinical examination - OSCE/n Smoking cessation checklist PHC Task Communication Score Weight Degree 1. Greeting (1) 2. Introducing self (1) 3. Personal data (Name, age, occupation and marital status) (4) /10 10% 4. Active listening& Keeping eyes contact (2) 5. Explores Patient reason for visit or 2 open ended questions (2) 5 As Counseling Approach Ask: 1. Type of smoking (2) 2. Frequency (2) 3. Duration (2) 4. Quitting history and causes of failure (2) 5. Morning Cigarette (1) 6. Patient's understanding of smoking associated health risks. (2) 7. Why he decided to give up smoking now? (1) Assist: 1. Set a quit date. (2) 2. Tell family, friends, co-workers (3) 3. Avoid situations that trigger smoking, go to smoke-free environments (2) 4. Anticipate challenges (cough, headache, increase appetite...) (2) /12 30% 5. Remove all cigarettes and cigarette products (2) 6. Keep busy (Exercise, go to a movie, take a walk) (2) /30 30 7. Compensate (candy, drink plenty of fluids, avoid alcohol). (2) 8. Counselling (Behavioral, Group, individual, Telephone) (4) 9. Nicotine replacement therapy (types, S/E, duration) (5) 10. Bupropion (S/E, duration) (3) 11. Varenicline (S/E, duration) (3) Total 60% Total Station ( ) Ali is a 52 years old man comes to the Primary Care Clinic for counseling to quit smoking. Task: Using 5 As model, ask and assist the patient to achieve his desire to quit smoking./n OMAIN Station for elderly care. You are approaching 70 years old man who has multiple chronic health problems and many medications. -At this station; focus on reviewing his medications in an appropriate way. ntroduction 2 3 ITEM Summarizing the professional standing End with a lead-in to the next part of the consultation Appropriate welcome, Student's perfor 0 1 2 3 VI Station an appropriate way. Student's performance DOMAIN Self-introduction 2 ITEM Summarizing the professional standing End with a lead-in to the next part of the consultation 0 1 2 3 4 5 3 Appropriate welcome, 4 use opened ended question 5 active listening Greeting the patient 6 eye to eye contact 7 pt. centered approach 8 How many medicines? 9 What are they? 10 How frequent are they used? Reviewing 11 of 12 medications 13 When to be taken? Self-taking/care giver? Let pt. demonstrate how to use. 14 Best doctor's response Total / 70% /3 marksSee Answer
Q5: INSTRUCTIONS This is a group project where they worked on it and some files are attached So basically our drug was Levetiracetam, then after doing the pivot table the most trending was levetiracetam induced spontaneous abortion (in pregnancy) Student part is to work on method result evaluation and discussion So basically for this one is to assess if levetiracetam can cause spontaneous abortion in pregnancy because from our pivot table i shared it had the most trending part, then talk about the methods u used assessing this and what are the limitations and strengths you had while assessing this then overal have a discussion of everything Need to create the MUE(Medication Use Evaluation) for this work, Need to do it in 1000 1100 words, APA StyleSee Answer

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